DOMINICA Trial
Phase 3
200
about 9.1 years
6–18
28 sites in AL, AR, AZ +16
About this study
This trial is testing benralizumab, a drug given by injection, in children with severe asthma. The goal is to see if benralizumab helps reduce the frequency of asthma attacks compared to a placebo.
Based on ClinicalTrials.gov records.
What participants do
- 1.Take Benralizumab
- 2.Take Placebo
Participation effort
Estimated from trial records. Details can vary by site.
Logistics difficulty varies by site location and availability.
Trial highlights
Treatment details
Auto-extracted from trial records to preview treatments and outcomes.
benralizumab
Secondary: Change from baseline, during the DB treatment period in Asthma symptom score, Change from baseline, during the DB treatment period in Interviewer-Administered Version of the Asthma Control Questionnaire (ACQ-IA), Change from baseline, during the DB treatment period in Paediatric Asthma Quality of Life Questionnaire-Interviewer Administered (PAQLQ-IA) total score, Change from baseline, during the DB treatment period in night-time awakenings due to asthma, Change from baseline, during the DB treatment period in peak expiratory flow (PEF), Change from baseline, during the DB treatment period in rescue medication use, Change from baseline, during the DB treatment period, in spirometry, for post-bronchodilator FEV1, Change from baseline, during the DB treatment period, in spirometry, for pre-dose/pre-bronchodilator forced expiratory volume in one second (FEV1)
Respiratory