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Study details
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Olanzapine for Cancer Appetite Loss

OHSU Knight Cancer Institute
NCT IDNCT05705492ClinicalTrials.gov data as of Apr 2026
Phase

Phase 2

Target enrollment

66

Study length

about 1.5 years

Ages

18+

Locations

1 site in OR

About this study

This trial is testing if olanzapine helps manage appetite loss in people with advanced cancers like esophageal, lung, or colon cancer. Olanzapine is a medication that may stimulate appetite and improve quality of life.

Based on ClinicalTrials.gov records.

What participants do

  • 1.Questionnaire Administration
  • 2.Take Olanzapine
  • 3.Take Placebo Administration
PhasePhase 2
DrugOlanzapine
Routeoral

Participation effort

Estimated from trial records. Details can vary by site.

Time + visits
Low15%
Logistics
Moderate50%

Logistics difficulty varies by site location and availability.

Trial highlights

Treatment details

Auto-extracted from trial records to preview treatments and outcomes.

Drug classes

olanzapine

Drug routes

oral (Oral Tablet)

Endpoints

Secondary: Change in Weight, Incidence of adverse events, Patient Reported Quality of Life, Patient Reported Symptoms, Physical Function, Proportion of patients with ≥1 unplanned hospitalization

Body systems

Oncology