Cardiovascular Effects of Very Low Nicotine Content Cigarettes
EARLY_PHASE1
49
about 3.7 years
21+
1 site in NC
About this study
Researchers are testing the cardiovascular effects of very low nicotine content cigarettes on smokers. The trial will measure changes in heart rate, autonomic functions, and indices of ventricular repolarization in participants who smoke two VLNCC and one NNCC while their ECG is recorded.
Based on ClinicalTrials.gov records.
What participants do
- 1.Take SPECTRUM cigarettes
- 2.Usual brand of Cigarettes
Participation effort
Estimated from trial records. Details can vary by site.
Logistics difficulty varies by site location and availability.
Trial highlights
Treatment details
Auto-extracted from trial records to preview treatments and outcomes.
Primary: Change in Heart rate - Normal Nicotine Content Cigarettes (NNCC)s - NRC600/601(15.8mg nicotine), Change in Heart rate - Very Low Nicotine Content Cigarettes (VLNCC)s - NRC102/103(0.5mg nicotine), Change in Heart rate - Very Low Nicotine Content Cigarettes (VLNCC)s - NRC301/302(2.4mg nicotine)
Secondary: Change in Heart rate variability(HRV) - Normal Nicotine Content Cigarettes (NNCC)s - NRC600/601(15.8mg nicotine), Change in Heart rate variability(HRV) - Very Low Nicotine Content Cigarettes (VLNCC)s - NRC102/103(0.5mg nicotine), Change in Heart rate variability(HRV) - Very Low Nicotine Content Cigarettes (VLNCC)s - NRC301/302(2.4mg nicotine)