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Study details
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Neurostimulation Versus Therapy for Problems With Emotions

Duke University
NCT IDNCT05712057ClinicalTrials.gov data as of Apr 2026
Target enrollment

240

Study length

about 4.1 years

Ages

18–55

Locations

1 site in NC

About this study

Researchers are testing whether a single session of neurostimulation, combined with emotion regulation training, helps people manage their emotions better than just using the neurostimulation alone. The trial also aims to find out how brain changes relate to who responds best to this type of treatment.

Based on ClinicalTrials.gov records.

What participants do

  • 1.Participate in Cognitive Restructuring
  • 2.Participate in Emotional Awareness Training
  • 3.Use Repetitive Transcranial Magnetic Stimulation (rTMS)
  • +1 more
Primary goalHigh Frequency Heart Rate Variability (HF-HRV) during regulation blocks during the neurostimulation day

Participation effort

Estimated from trial records. Details can vary by site.

Time + visits
Low9%
Logistics
Moderate50%

Logistics difficulty varies by site location and availability.

Trial highlights

Treatment details

Auto-extracted from trial records to preview treatments and outcomes.

Endpoints

Primary: High Frequency Heart Rate Variability (HF-HRV) during regulation blocks during the neurostimulation day, Time to return to Heart Rate (HR) baseline measured during regulation period

Secondary: Self Efficacy with Emotion Regulation (PROMIS-SEME)

Devices

therapeutic

Body systems

Psychiatry / Mental Health