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Study details
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A Study to Investigate the Safety and Tolerability of Ziftomenib in Combination With Venetoclax/Azacitidine, Venetoclax, 7+3, or 7+3+Quizartinib in Patients With AML

Kura Oncology, Inc.
NCT IDNCT05735184ClinicalTrials.gov data as of Apr 2026
Phase

Phase 1

Target enrollment

420

Study length

about 6.8 years

Ages

18+

Locations

44 sites in AZ, CA, CO +21

About this study

This trial is testing a treatment called ziftomenib when combined with other medications to treat acute myeloid leukemia (AML). The goal is to see if the treatment is safe and well-tolerated.

Based on ClinicalTrials.gov records.

What participants do

  • 1.Take Azacitidine
  • 2.Take Cytarabine
  • 3.Take Daunorubicin
  • +3 more
PhasePhase 1
DrugAzacitidine
Routeinjection
Primary goalComplete remission (CR) rate

Participation effort

Estimated from trial records. Details can vary by site.

Time + visits
Low11%
Logistics
Moderate50%

Logistics difficulty varies by site location and availability.

Trial highlights

Treatment details

Auto-extracted from trial records to preview treatments and outcomes.

Drug classes

azacitidine, cytarabine, daunorubicin, quizartinib, venetoclax

Drug routes

injection, subcutaneous, injection (Injection), oral (Oral Tablet), oral, oral (Oral Capsule)

Endpoints

Primary: Complete remission (CR) rate, Descriptive statistics of adverse events

Secondary: Cmax, Cmax of quizartinib, Cmax of venetoclax, EFS, Median DOR, Median EFS, Median OS, Tmax

Body systems

Oncology