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Study details
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Diet Interventions: Remitted and Evaluated as Complementary Treatments for Pain

University of Alabama at Birmingham
NCT IDNCT05785884ClinicalTrials.gov data as of Apr 2026
Target enrollment

200

Study length

about 4.4 years

Ages

40–75

Locations

1 site in AL

About this study

Researchers are testing whether a low-carbohydrate diet can help reduce pain in people with osteoarthritis of the knee. The trial will provide all meals to participants to ensure they follow the diet, which should improve the results compared to previous studies. Participants will be adults with knee OA who are asked to complete two phases: a run-up week and a 6-week randomized diet intervention.

Based on ClinicalTrials.gov records.

What participants do

  • 1.Participate in Diet
Primary goalBPI pain change

Participation effort

Estimated from trial records. Details can vary by site.

Time + visits
Low7%
Logistics
Moderate50%

Logistics difficulty varies by site location and availability.

Trial highlights

Treatment details

Auto-extracted from trial records to preview treatments and outcomes.

Endpoints

Primary: BPI pain change, TUG pain intensity change, Western Ontario and McMaster Osteoarthritis Index pain change

Secondary: BPI pain interference change, PHQ-9 Depression change, Repeated Chair Stand pain intensity change, SF-36 Quality of Life change, Temporal Summation pain intensity change

Body systems

Musculoskeletal