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Study details
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Emergency Department Medications for Alcohol Use Disorder

Yale University
NCT IDNCT05827159ClinicalTrials.gov data as of Apr 2026
Phase

Phase 3

Target enrollment

240

Study length

about 3.5 years

Ages

18–80

Locations

1 site in CT

About this study

This trial is testing a new way to treat moderate to severe alcohol use disorder (AUD) in the emergency department. It combines brief counseling with medications like naltrexone or gabapentin, given as an injection or pill. The goal is to see if this approach helps people stay engaged in treatment and reduce heavy drinking days after their visit to the ED.

Based on ClinicalTrials.gov records.

What participants do

  • 1.Participate in Brief Negotiation Interview
  • 2.Receive Naltrexone Injection
  • 3.Take Gabapentin Pill
  • +1 more
PhasePhase 3
DrugGabapentin Pill
Routeoral

Participation effort

Estimated from trial records. Details can vary by site.

Time + visits
Low11%
Logistics
Moderate50%

Logistics difficulty varies by site location and availability.

Trial highlights

Treatment details

Auto-extracted from trial records to preview treatments and outcomes.

Drug classes

anticonvulsant (Modulates calcium channels; used for neuropathic pain and seizures), naltrexone, NERVOUS SYSTEM

Drug routes

oral (Oral Tablet), injection, intramuscular, injection (Injection), oral

Endpoints

Secondary: Alcohol withdrawal symptoms

Body systems

Psychiatry / Mental Health