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Study details
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Efficacy and Safety of Magnesium Vitamin B6 in First Episode Bipolar Disorder

Mclean Hospital
NCT IDNCT05837104ClinicalTrials.gov data as of Apr 2026
Phase

Phase 2

Target enrollment

40

Study length

about 2.1 years

Ages

18–50

Locations

1 site in MA

About this study

Researchers are testing whether magnesium vitamin B6, combined with usual treatment, can help reduce symptoms of depression, stress, and anxiety in people experiencing their first episode of bipolar I disorder. The trial will last for 749 days.

Based on ClinicalTrials.gov records.

What participants do

  • 1.Take Magnesium vitamin B6
  • 2.Take Placebo
PhasePhase 2
DrugMagnesium vitamin B6
Routeoral
Primary goalChange in depressive symptoms

Participation effort

Estimated from trial records. Details can vary by site.

Time + visits
Low10%
Logistics
Moderate50%

Logistics difficulty varies by site location and availability.

Trial highlights

Treatment details

Auto-extracted from trial records to preview treatments and outcomes.

Drug classes

Enzyme Interactions

Drug routes

oral (Oral Tablet)

Endpoints

Primary: Change in depressive symptoms

Secondary: Change in adverse events, Change in anxiety symptoms, Change in stress symptoms

Body systems

Psychiatry / Mental Health