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Study details
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A Phase 1 Clinical Trial of NXP900 in Subjects With Advanced Cancers

Nuvectis Pharma, Inc.
NCT IDNCT05873686ClinicalTrials.gov data as of Apr 2026
Phase

Phase 1

Target enrollment

140

Study length

about 3.8 years

Ages

18+

Locations

10 sites in AZ, CO, FL +5

About this study

Researchers are testing a new treatment, NXP900, for advanced cancers. The trial will start with a small group of people to determine the best dose and then expand to more participants.

Based on ClinicalTrials.gov records.

What participants do

  • 1.Take NXP900
PhasePhase 1
Primary goalNumber of patients with treatment related adverse events and/or clinical laboratory abnormalities

Participation effort

Estimated from trial records. Details can vary by site.

Time + visits
Low14%
Logistics
Moderate50%

Logistics difficulty varies by site location and availability.

Trial highlights

Treatment details

Auto-extracted from trial records to preview treatments and outcomes.

Endpoints

Primary: Number of patients with treatment related adverse events and/or clinical laboratory abnormalities, Part A: Number of patients who experience Dose Limiting Toxicities (DLT) as defined in the protocol, Part B: Disease Control Rate (DCR), Part B: Duration of Response (DoR), Part B: Objective response rate (ORR)

Secondary: Apparent plasma clearance at steady state (Clss/F) of NXP900, Area under the concentration-time curve (AUC) of NXP900, Half-life (T1/2) of NXP900, Maximum observed concentration (Cmax) of NXP900, Time to peak concentration (Tmax) of NXP900

Body systems

Oncology, Respiratory