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Study details
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Preemptive Ibuprofen Effects on Pain Perception Following Extraction and Bone Graft

Marquette University
NCT IDNCT05919745ClinicalTrials.gov data as of Apr 2026
Phase

Phase 4

Target enrollment

50

Study length

about 3.2 years

Ages

18+

Locations

1 site in WI

About this study

Researchers are testing if taking ibuprofen before a tooth extraction with bone graft surgery helps reduce pain compared to not taking anything. The trial will last 1169 days, and it's for adults. Participants will receive either ibuprofen or a placebo.

Based on ClinicalTrials.gov records.

What participants do

  • 1.Take Acetaminophen
  • 2.Take Ibuprofen 600 mg
  • 3.Take Placebo
PhasePhase 4
DrugAcetaminophen
Routeoral
Primary goalDifference in patient-reported postoperative pain between test and control group

Participation effort

Estimated from trial records. Details can vary by site.

Time + visits
Low15%
Logistics
Moderate50%

Logistics difficulty varies by site location and availability.

Trial highlights

Treatment details

Auto-extracted from trial records to preview treatments and outcomes.

Drug classes

paracetamol (Reduces fever and pain (mechanism not fully understood)), ibuprofen

Drug routes

oral

Endpoints

Primary: Difference in patient-reported postoperative pain between test and control group

Secondary: Difference in patient-reported postoperative pain between test and control group