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Study details
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IN Midazolam vs IN Dexmedetomidine vs IN Ketamine During Minimal Procedures in Pediatric ED

University of Oklahoma
NCT IDNCT05934669ClinicalTrials.gov data as of Apr 2026
Phase

Phase 4

Target enrollment

90

Study length

about 1.6 years

Ages

1–5

Locations

1 site in OK

About this study

This trial is testing whether intranasal midazolam, dexmedetomidine, or ketamine are better for children who need minor procedures like laceration repairs. The goal is to see which medication helps kids stay calm and have a shorter time in the emergency department while also making both patients and doctors happy.

Based on ClinicalTrials.gov records.

What participants do

  • 1.Take Intranasal Dexmedetomidine
  • 2.Take Intranasal Ketamine
  • 3.Take Intranasal Midazolam
PhasePhase 4
DrugIntranasal Dexmedetomidine

Participation effort

Estimated from trial records. Details can vary by site.

Time + visits
Low8%
Logistics
Moderate50%

Logistics difficulty varies by site location and availability.

Trial highlights

Treatment details

Auto-extracted from trial records to preview treatments and outcomes.

Drug classes

dexmedetomidine, ketamine (NMDA receptor antagonist; induces dissociative anesthesia and analgesia), midazolam (Benzodiazepine; short-acting)

Drug routes

intranasal, injection

Body systems

Dermatology, Psychiatry / Mental Health