Study details
Enrolling now
Breathe Easier With Tadalafil Therapy for Dyspnea in COPD-PH
VA Office of Research and Development
NCT IDNCT05937854ClinicalTrials.gov data as of Apr 2026
Phase
Phase 2
Target enrollment
126
Study length
about 3.7 years
Ages
35–89
Locations
5 sites in CO, GA, MA +2
About this study
Researchers are testing whether tadalafil, a medication, improves shortness of breath in Veterans with Chronic Obstructive Pulmonary Disease (COPD) and high blood pressure in the lungs. The trial will also assess if tadalafil improves quality of life, exercise endurance, and other health measures.
Based on ClinicalTrials.gov records.
What participants do
- 1.Take Placebo
- 2.Take Tadalafil
PhasePhase 2
DrugTadalafil
Routeoral
Participation effort
Estimated from trial records. Details can vary by site.
Time + visits
Low15%
Logistics
Moderate50%
Logistics difficulty varies by site location and availability.
Trial highlights
Treatment details
Auto-extracted from trial records to preview treatments and outcomes.
Drug classes
tadalafil
Drug routes
oral (Oral Tablet)
Endpoints
Secondary: physical activity
Body systems
Respiratory