Skip to content
Study details
Enrolling now

The Osteoarthritis Prevention Study

Wake Forest University
NCT IDNCT05946044ClinicalTrials.gov data as of Apr 2026
Target enrollment

1,230

Study length

about 5.4 years

Ages

50+

Sex

Female only

Locations

3 sites in MA, NC

About this study

Researchers are testing if a diet and exercise program can help prevent osteoarthritis in women aged 50 or older who are obese. The trial will compare this approach to not doing anything (a control group) over several years.

Based on ClinicalTrials.gov records.

What participants do

  • 1.Participate in Diet and Exercise
Primary goalStructural knee Osteoarthritis (OA) MRI change Scores

Participation effort

Estimated from trial records. Details can vary by site.

Time + visits
Low9%
Logistics
Moderate50%

Logistics difficulty varies by site location and availability.

Trial highlights

Treatment details

Auto-extracted from trial records to preview treatments and outcomes.

Endpoints

Primary: Structural knee Osteoarthritis (OA) MRI change Scores

Secondary: Health-Related Quality of Life Scores, Knee Pain Scores

Body systems

Musculoskeletal