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Study details
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Autologous Adipose-Derived Mesenchymal Stem Cells for Chronic Traumatic Brain Injury

Hope Biosciences LLC
NCT IDNCT05951777ClinicalTrials.gov data as of Apr 2026
Phase

Phase 2

Target enrollment

51

Study length

about 2.7 years

Ages

18–55

Locations

2 sites in TX

About this study

Researchers are testing a treatment with autologous HB-adMSCs to see if it can improve brain structure, cognitive function, and reduce inflammation after traumatic brain injury. The trial will last about 989 days.

Based on ClinicalTrials.gov records.

What participants do

  • 1.Receive Autologous HB-adMSCs
  • 2.Take Normal Saline
PhasePhase 2
DrugNormal Saline
Primary goalAlanine aminotransferase

Participation effort

Estimated from trial records. Details can vary by site.

Time + visits
Low15%
Logistics
Moderate50%

Logistics difficulty varies by site location and availability.

Trial highlights

Treatment details

Auto-extracted from trial records to preview treatments and outcomes.

Endpoints

Primary: Alanine aminotransferase, Aspartate aminotransferase, Creatinine, Glucose

Secondary: Brief Symptom Inventory 18, Interleukin 6, PET/DT-MRI (positron emission tomography/Diffusion tensor-Magnetic resonance imaging), TBI (Traumatic Brain Injury) Quality of Life Questionnaires, Whole brain MRI (Magnetic resonance imaging)