A Study to Investigate the Efficacy and Safety of Tezepelumab Compared With Placebo in Children 5 to < 12 Years Old With Severe Asthma
Phase 3
231
about 7 years
5–11
30 sites in AL, AR, AZ +12
About this study
This trial is testing a treatment called tezepelumab compared to a placebo (inactive pill) in children with severe asthma. The goal is to see if tezepelumab helps improve asthma control and is safe for this age group.
Based on ClinicalTrials.gov records.
What participants do
- 1.Placebo
- 2.Receive Tezepelumab
Participation effort
Estimated from trial records. Details can vary by site.
Logistics difficulty varies by site location and availability.
Trial highlights
Treatment details
Auto-extracted from trial records to preview treatments and outcomes.
tezepelumab
Secondary: Change from baseline in Asthma Control Questionnaire - Interviewer Administered (ACQ-IA) score, Change from baseline in Paediatric Asthma Quality of Life Questionnaire (PAQLQ-(S)-IA) total score, Change from baseline in blood eosinophil count, Change from baseline in fractional exhaled nitric oxide (FeNO), Change from baseline in pre-bronchodilator (pre-BD) forced expiratory volume in 1 second (FEV1) percent predicted normal (PN), Change from baseline in pre-bronchodilator (pre-BD) peak expiratory flow (PEF), Change from baseline in total serum IgE, Change from baseline in weekly mean daily Paediatric Asthma Symptom Observer (PASO) score
Respiratory