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Study details
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Amplification of Positivity for Alcohol Use

Laureate Institute for Brain Research, Inc.
NCT IDNCT06030154ClinicalTrials.gov data as of Apr 2026
Target enrollment

100

Study length

about 2.8 years

Ages

18–65

Locations

1 site in OK

About this study

Researchers are testing a new treatment called Amplification of Positivity Therapy to help people with alcohol use disorder, anxiety, and depression. Participants will be asked about their experiences with the therapy, which may lead to changes in the treatment itself. The trial will also compare this therapy to Cognitive Behavioral Therapy (CBT) for individuals experiencing these conditions.

Based on ClinicalTrials.gov records.

What participants do

  • 1.Participate in Amplification of Positivity Therapy
  • 2.Participate in Cognitive Behavioral Therapy
  • 3.Participate in Surveys and Interviews
Primary goalChange in positive affect self-report measured with National Institute of Health (NIH) Patient Reported Outcome Measurement and Information System (PROMIS) Positive Affect score

Participation effort

Estimated from trial records. Details can vary by site.

Time + visits
Low9%
Logistics
Moderate50%

Logistics difficulty varies by site location and availability.

Trial highlights

Treatment details

Auto-extracted from trial records to preview treatments and outcomes.

Endpoints

Primary: Change in positive affect self-report measured with National Institute of Health (NIH) Patient Reported Outcome Measurement and Information System (PROMIS) Positive Affect score

Secondary: Change in Patient-Reported Outcomes Measurement Information System (PROMIS) Anxiety Scale, Change in Patient-Reported Outcomes Measurement Information System (PROMIS) Depression Scale, Change in the Patient-Reported Outcomes Measurement Information System (PROMIS) Meaning and Purpose Scale

Procedures

therapy

Body systems

Psychiatry / Mental Health