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Study details
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Mezigdomide (CC-92480) Post Idecabtagene Vicleucel in Treating Patients With Relapsed Multiple Myeloma

City of Hope Medical Center
NCT IDNCT06048250ClinicalTrials.gov data as of Apr 2026
Phase

Phase 1

Target enrollment

15

Study length

about 1.9 years

Ages

18+

Locations

1 site in CA

About this study

This trial is testing the safety, side effects, best dose and effectiveness of mezigdomide (CC-92480) when given after idecabtagene vicleucel (Abecma chimeric antigen receptor [CAR] T-cell therapy) in patients with multiple myeloma that has come back after a period of improvement (relapsed). Mezigdomide may extend the time CAR T cells persist in the body in relapsed multiple myeloma.

Based on ClinicalTrials.gov records.

What participants do

  • 1.Receive Mezigdomide
  • 2.Undergo Biospecimen Collection
  • 3.Undergo Bone Marrow Aspiration
  • +2 more
PhasePhase 1
DrugMezigdomide
Primary goalIncidence of adverse events

Participation effort

Estimated from trial records. Details can vary by site.

Time + visits
Low14%
Logistics
Moderate50%

Logistics difficulty varies by site location and availability.

Trial highlights

Treatment details

Auto-extracted from trial records to preview treatments and outcomes.

Endpoints

Primary: Incidence of adverse events

Secondary: Complete response rate, Duration of response, Overall response rate, Overall survival, Progression free survival, Time to progression

Procedures

diagnostic, biopsy, imaging

Body systems

Oncology