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Study details
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MDMA-assisted Therapy for Fibromyalgia

Spaulding Rehabilitation Hospital
NCT IDNCT06066853ClinicalTrials.gov data as of Apr 2026
Phase

EARLY_PHASE1

Target enrollment

20

Study length

about 12 months

Ages

21–65

Locations

1 site in MA

About this study

Researchers are testing if MDMA-assisted therapy can help people with fibromyalgia. The trial will involve two sessions of MDMA combined with neuroimaging and integrative therapy, along with baseline and follow-up imaging. The goal is to see how this treatment affects the patient-clinician relationship and brain activity in these patients.

Based on ClinicalTrials.gov records.

What participants do

  • 1.Take MDMA
PhaseEARLY_Phase 1
Routeoral
Primary goalChange in self-reported pain severity and pain interference (Brief Pain Inventory)

Participation effort

Estimated from trial records. Details can vary by site.

Time + visits
Low13%
Logistics
Moderate50%

Logistics difficulty varies by site location and availability.

Trial highlights

Treatment details

Auto-extracted from trial records to preview treatments and outcomes.

Drug routes

oral

Endpoints

Primary: Change in self-reported pain severity and pain interference (Brief Pain Inventory)

Body systems

Musculoskeletal