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Study details
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Examining Neurobiological Mechanisms Underlying the Therapeutic Effect of the Ketogenic Diet in Bipolar Disorder (BD)

University of Pittsburgh
NCT IDNCT06081426ClinicalTrials.gov data as of Apr 2026
Target enrollment

107

Study length

about 3.1 years

Ages

18–40

Locations

1 site in PA

About this study

This trial is testing if a ketogenic diet affects brain activity and metabolism in adults with bipolar disorder. The goal is to see how changes in ketone levels might reduce mania or hypomania.

Based on ClinicalTrials.gov records.

What participants do

  • 1.Ketogenic Diet
  • 2.No diet
  • 3.Non-ketogenic Diet
Primary goalManic symptoms at Scan 1

Participation effort

Estimated from trial records. Details can vary by site.

Time + visits
Low11%
Logistics
Moderate50%

Logistics difficulty varies by site location and availability.

Trial highlights

Treatment details

Auto-extracted from trial records to preview treatments and outcomes.

Endpoints

Primary: Manic symptoms at Scan 1, Manic symptoms at Scan 2, Manic symptoms at Scan 3

Body systems

Psychiatry / Mental Health