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Study details
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Moderate Versus High Volume Light-Moderate Intensity Exercise for People With Moderate Parkinson's Disease

VA Office of Research and Development
NCT IDNCT06088355ClinicalTrials.gov data as of Apr 2026
Target enrollment

123

Study length

about 4.4 years

Ages

40+

Locations

1 site in GA

About this study

This trial is testing whether working out more often with breaks or exercising continuously is better at preventing brain cell loss in people with moderate Parkinson's disease. The researchers will measure how fast participants walk, their physical activity levels, blood chemicals, and the stiffness of their blood vessels before and after exercise.

Based on ClinicalTrials.gov records.

What participants do

  • 1.Participate in HV-PDAE: High Volume Partnered Dance Aerobic Exercise
  • 2.Participate in MV-PDAE: Moderate Volume Partnered Dance Aerobic Exercise
  • 3.Participate in MV-WALK: Moderate Volume Walking
Primary goalvascular function: Pulse wave velocity and Aortic index

Participation effort

Estimated from trial records. Details can vary by site.

Time + visits
Low9%
Logistics
Moderate50%

Logistics difficulty varies by site location and availability.

Trial highlights

Treatment details

Auto-extracted from trial records to preview treatments and outcomes.

Endpoints

Primary: vascular function: Pulse wave velocity and Aortic index

Secondary: Six minute walk test, inflammatory cytokine expression: Brain derived neurotrophic factor and c-reactive protein, inflammatory cytokine expression: and c reactive protein

Body systems

Neurology