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Study details
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AZD0305 Trial

AstraZeneca
NCT IDNCT06106945ClinicalTrials.gov data as of Apr 2026
Phase

Phase 1/2

Target enrollment

226

Study length

about 3.3 years

Ages

18+

Locations

9 sites in CA, GA, MA +5

About this study

Researchers are testing AZD0305 as a treatment for relapsed/refractory multiple myeloma. The trial will evaluate the safety, tolerability, and effectiveness of AZD0305 in adults with this condition.

Based on ClinicalTrials.gov records.

What participants do

  • 1.Take AZD0305
PhasePhase 1/Phase 2
Primary goalIncidence and severity of Adverse Events (AEs) and Serious Adverse Events (SAEs)

Participation effort

Estimated from trial records. Details can vary by site.

Time + visits
Low6%
Logistics
Moderate50%

Logistics difficulty varies by site location and availability.

Trial highlights

Treatment details

Auto-extracted from trial records to preview treatments and outcomes.

Endpoints

Primary: Incidence and severity of Adverse Events (AEs) and Serious Adverse Events (SAEs), Occurrence of dose-limiting toxicity (DLT), as defined in the protocol (Phase Ia dose escalation only)

Secondary: Phase Ia: Duration of response (DoR), Phase Ia: Objective Response Rate (ORR), Phase Ia: Overall Survival (OS), Phase Ia: Pharmacokinetics of AZD0305: Area Under the concentration-time curve (AUC), Phase Ia: Pharmacokinetics of AZD0305: Clearance, Phase Ia: Pharmacokinetics of AZD0305: Maximum plasma concentration of the study drug (Cmax), Phase Ia: Pharmacokinetics of AZD0305: Terminal elimination half-life (t 1/2), Phase Ia: Pharmacokinetics of AZD0305: Time to maximum plasma concentration of the study drug (tmax)

Body systems

Oncology