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Study details
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Dupilumab De-escalation in Pediatric Atopic Dermatitis

Johns Hopkins University
NCT IDNCT06116526ClinicalTrials.gov data as of Apr 2026
Phase

Phase 4

Target enrollment

30

Study length

about 3.1 years

Ages

1–17

Locations

1 site in MD

About this study

Researchers are testing whether children with atopic dermatitis can stop or reduce their dupilumab treatment if they have achieved good control of their skin condition. The trial will last for 1124 days and involve approximately 30 children aged 1 to 17 years.

Based on ClinicalTrials.gov records.

What participants do

  • 1.Take Dupilumab - Discontinuation
  • 2.Take Dupilumab - Dose Reduction
  • 3.Take Dupilumab - Standard Dose
PhasePhase 4
DrugDupilumab - Standard Dose

Participation effort

Estimated from trial records. Details can vary by site.

Time + visits
Low6%
Logistics
Moderate50%

Logistics difficulty varies by site location and availability.

Trial highlights

Treatment details

Auto-extracted from trial records to preview treatments and outcomes.

Endpoints

Secondary: Adverse Events After Dupilumab Dose-reduction or Discontinuation, Change in Patient-Reported Outcomes Measurement Information System (PROMIS) Anxiety questionnaire score, Change in Patient-Reported Outcomes Measurement Information System (PROMIS) Cognitive Function questionnaire score, Change in Patient-Reported Outcomes Measurement Information System (PROMIS) Depressive Symptoms questionnaire score, Change in Patient-Reported Outcomes Measurement Information System (PROMIS) Global Health questionnaire score, Change in Patient-Reported Outcomes Measurement Information System (PROMIS) Itch questionnaire score, Change in Patient-Reported Outcomes Measurement Information System (PROMIS) Pain Intensity questionnaire score, Change in Patient-Reported Outcomes Measurement Information System (PROMIS) Sleep Problem questionnaire score

Body systems

Dermatology