Correcting Circadian Rhythms to Breakthrough in Bipolar Disorder
Phase 2
50
about 1.7 years
18–60
1 site in MI
About this study
This trial is testing whether a dietary supplement (low-dose melatonin) will help shift the brain clock earlier and improve mood and sleep in people with bipolar disorder. Participants will receive either melatonin plus a behavioral sleep intervention or a placebo plus a behavioral sleep placebo for 625 days.
Based on ClinicalTrials.gov records.
What participants do
- 1.Participate in Behavioral sleep control
- 2.Participate in Behavioral sleep intervention
- 3.Placebo
- +1 more
Participation effort
Estimated from trial records. Details can vary by site.
Logistics difficulty varies by site location and availability.
Trial highlights
Treatment details
Auto-extracted from trial records to preview treatments and outcomes.
melatonin (Hormone supplement; regulates sleep-wake cycle)
oral (Disintegrating Oral Tablet)
Secondary: Change in the Patient Health Questionnaire-9 (PHQ-9)
Psychiatry / Mental Health