Androgen Suppression Combined With Nodal Irradiation and Dose Escalated Prostate Treatment
Phase 3
710
about 9 years
18+
Male only
46 sites in CA, IL, MO +4
About this study
This trial is testing whether a new way of giving radiation therapy, called SBRT, is as effective as usual radiation therapy for prostate cancer. The treatment involves suppressing testosterone levels with medication (ADT) along with radiation therapy and brachytherapy.
Based on ClinicalTrials.gov records.
What participants do
- 1.Receive Radiation
- 2.Receive Radiation SBRT only
- 3.Take ADT
Participation effort
Estimated from trial records. Details can vary by site.
Logistics difficulty varies by site location and availability.
Trial highlights
Treatment details
Auto-extracted from trial records to preview treatments and outcomes.
hormone therapy
Primary: To compare the progression-free survival (PFS) of SBRT versus conventional EBRT plus brachytherapy boost defined as time to biochemical failure, initiation of salvage therapy, local-regional recurrence, distant progression, or death
Secondary: Economic Outcomes using EQ-5D-5L, Economic Outcomes using FACIT-COST, Overall Survival analysed using a Cox proportional hazards model and graphically described using the Kaplan-Meier method, Participant-reported tolerability using PRO-CTCAE questionnaire, Safety and tolerability assessed by CTCAE v5.0
radiation
Oncology