Skip to content
Study details
Enrolling now

A Phase 1/1b Study of IAM1363 in HER2 Cancers

Iambic Therapeutics, Inc
NCT IDNCT06253871ClinicalTrials.gov data as of Apr 2026
Phase

Phase 1

Target enrollment

243

Study length

about 4 years

Ages

18+

Locations

29 sites in CA, CO, FL +15

About this study

Researchers are testing a treatment called IAM1363 to see if it's safe and effective for people with advanced cancers that have HER2 changes. The trial will involve adults, and the estimated length of it is 1467 days.

Based on ClinicalTrials.gov records.

What participants do

  • 1.Take IAM1363
PhasePhase 1
Primary goalConfirmed central nervous system ORR (CNS-cORR)

Participation effort

Estimated from trial records. Details can vary by site.

Time + visits
Low11%
Logistics
Moderate50%

Logistics difficulty varies by site location and availability.

Trial highlights

Treatment details

Auto-extracted from trial records to preview treatments and outcomes.

Endpoints

Primary: Confirmed central nervous system ORR (CNS-cORR), Confirmed objective response rate (cORR), Incidence and severity of adverse events (AEs), Pharmacokinetic (PK) parameters

Secondary: Best overall response (BoR) rate, Clinical benefit rate (CBR), Disease control rate (DCR), Duration of response (DoR), Overall survival (OS), Progression-free survival (PFS)

Body systems

Oncology, Neurology