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Study details
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Beta-Blocker Influences on Inflammatory and Neural Responses to Stress

University of North Carolina, Chapel Hill
NCT IDNCT06263452ClinicalTrials.gov data as of Apr 2026
Phase

Phase 4

Target enrollment

120

Study length

about 2.1 years

Ages

18–30

Locations

1 site in NC

About this study

This trial is testing if a beta-blocker can change how your body reacts to stress, specifically in terms of inflammation and nerve activity. The goal is to understand these changes better so that new treatments for heart disease can be developed.

Based on ClinicalTrials.gov records.

What participants do

  • 1.Take Placebo
  • 2.Take Propranolol
PhasePhase 4
DrugPropranolol
Primary goalChange in levels of inflammatory gene expression in response to social stress

Participation effort

Estimated from trial records. Details can vary by site.

Time + visits
Low12%
Logistics
Moderate50%

Logistics difficulty varies by site location and availability.

Trial highlights

Treatment details

Auto-extracted from trial records to preview treatments and outcomes.

Drug classes

propranolol (Non-selective beta blocker; slows heart rate)

Endpoints

Primary: Change in levels of inflammatory gene expression in response to social stress, Change in levels of pro-inflammatory cytokine interleukin-6 in response to social stress

Body systems

Cardiology / Heart