Skip to content
Study details
Enrolling now

Intermittent Theta Burst Stimulation (iTBS) for Emotion Regulation in Bipolar Disorder

Massachusetts General Hospital
NCT IDNCT06274567ClinicalTrials.gov data as of Apr 2026
Target enrollment

136

Study length

about 4.5 years

Ages

24–65

Locations

2 sites in MA, PA

About this study

This trial is testing whether intermittent theta-burst transcranial magnetic stimulation (iTBS-TMS) can improve emotion regulation in people with bipolar disorder. The treatment involves using a device to stimulate specific areas of the brain, and researchers will compare this to a sham treatment.

Based on ClinicalTrials.gov records.

What participants do

  • 1.Use Sham (placebo) TMS
  • 2.Use Transcranial Magnetic Stimulation (TMS)
Primary goalCorrelated functional magnetic resonance imaging (fMRI) time series (functional connectivity)

Participation effort

Estimated from trial records. Details can vary by site.

Time + visits
Low7%
Logistics
Moderate50%

Logistics difficulty varies by site location and availability.

Trial highlights

Treatment details

Auto-extracted from trial records to preview treatments and outcomes.

Endpoints

Primary: Correlated functional magnetic resonance imaging (fMRI) time series (functional connectivity)

Devices

therapeutic

Body systems

Psychiatry / Mental Health