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Study details
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A Study of CBX-12 in Subjects With Platinum Resistant or Refractory Ovarian Cancer

Cybrexa Therapeutics
NCT IDNCT06315491ClinicalTrials.gov data as of Apr 2026
Phase

Phase 2

Target enrollment

40

Study length

about 1.1 years

Ages

18+

Sex

Female only

Locations

17 sites in AZ, CA, CT +10

About this study

This trial is testing a treatment called CBX-12 in women with ovarian cancer that has not responded to platinum chemotherapy. The goal is to see if this treatment is safe and effective.

Based on ClinicalTrials.gov records.

What participants do

  • 1.Take CBX-12
PhasePhase 2
Primary goalPercentage of Subjects With Complete Response (CR) or Partial Response (PR) [Objective Response Rate (ORR)]

Participation effort

Estimated from trial records. Details can vary by site.

Time + visits
Low8%
Logistics
Moderate50%

Logistics difficulty varies by site location and availability.

Trial highlights

Treatment details

Auto-extracted from trial records to preview treatments and outcomes.

Endpoints

Primary: Percentage of Subjects With Complete Response (CR) or Partial Response (PR) [Objective Response Rate (ORR)]

Secondary: Incidence of Subjects With Treatment Emergent Adverse Events (TEAEs), Median Duration of Response (DoR), Plasma levels of CBX-12 (Cmax), Plasma levels of CBX-12 (Tmax), Plasma levels of Exatecan (Cmax), Plasma levels of Exatecan (Tmax), Progression-Free Survival (PFS)

Body systems

Oncology