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Study details
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Axatilimab Trial

OHSU Knight Cancer Institute
NCT IDNCT06320405ClinicalTrials.gov data as of Apr 2026
Phase

Phase 1/2

Target enrollment

38

Study length

about 4.9 years

Ages

18+

Locations

1 site in OR

About this study

This trial is testing the safety, side effects, and effectiveness of axatilimab when combined with retifanlimab and paclitaxel for people with advanced or metastatic solid tumors. Axatilimab is a monoclonal antibody that may interfere with tumor growth and spread. Retifanlimab helps the immune system attack cancer cells, and paclitaxel stops cancer cell growth and division. This combination treatment aims to be safe, tolerable, and potentially effective in treating these cancers.

Based on ClinicalTrials.gov records.

What participants do

  • 1.Receive Axatilimab
  • 2.Receive Retifanlimab
  • 3.Take Paclitaxel
  • +3 more
PhasePhase 1/Phase 2
DrugAxatilimab
Routeinjection

Participation effort

Estimated from trial records. Details can vary by site.

Time + visits
Low15%
Logistics
Moderate50%

Logistics difficulty varies by site location and availability.

Trial highlights

Treatment details

Auto-extracted from trial records to preview treatments and outcomes.

Drug classes

Anti-inflammatory Agent (Colony Stimulating Factor Receptor Type 1 (CSF-1R) Inhibitors), paclitaxel (Taxane chemotherapy; stabilizes microtubules), retifanlimab

Drug routes

injection, intravenous

Procedures

biopsy, diagnostic, imaging

Body systems

Oncology