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Study details
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Suvorexant and Alcohol

William Stoops
NCT IDNCT06326684ClinicalTrials.gov data as of Apr 2026
Phase

EARLY_PHASE1

Target enrollment

30

Study length

about 2.8 years

Ages

21–55

Locations

1 site in KY

About this study

This trial is testing whether suvorexant, a medication, helps reduce alcohol cravings and other related behaviors in people with Alcohol Use Disorder. The goal is to understand how orexin affects alcohol addiction in humans. This research will provide initial clinical evidence on the effects of orexin antagonism on alcohol motivation.

Based on ClinicalTrials.gov records.

What participants do

  • 1.Take Alcohol
  • 2.Take Placebo
  • 3.Take Suvorexant
PhaseEARLY_Phase 1
DrugAlcohol

Participation effort

Estimated from trial records. Details can vary by site.

Time + visits
Low10%
Logistics
Moderate50%

Logistics difficulty varies by site location and availability.

Trial highlights

Treatment details

Auto-extracted from trial records to preview treatments and outcomes.

Drug classes

ethanol, suvorexant

Drug routes

oral (Oral Tablet)

Endpoints

Secondary: Blood pressure, Heart rate, Mood

Body systems

Psychiatry / Mental Health