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Study details
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Opioid Sparing Anesthesia Care for Pediatric Patients Having Tonsil Surgery

Boston Children's Hospital
NCT IDNCT06326983ClinicalTrials.gov data as of Apr 2026
Target enrollment

58

Study length

about 1.9 years

Ages

3–17

Locations

1 site in MA

About this study

This trial is testing if a plan using dexmedetomidine, ketorolac and acetaminophen is as good or better than a plan using morphine, ketorolac and acetaminophen for children having tonsil surgery. The goal is to see if this opioid-sparing approach helps with pain after surgery and how quickly kids recover.

Based on ClinicalTrials.gov records.

What participants do

  • 1.Take Acetaminophen
  • 2.Take Dexmedetomidine
  • 3.Take Ketorolac
  • +1 more
DrugAcetaminophen
Routeoral
Primary goalMedian Pain Scores in the Post-Anesthesia Care Unit

Participation effort

Estimated from trial records. Details can vary by site.

Time + visits
Low4%
Logistics
Moderate50%

Logistics difficulty varies by site location and availability.

Trial highlights

Treatment details

Auto-extracted from trial records to preview treatments and outcomes.

Drug classes

paracetamol (Reduces fever and pain (mechanism not fully understood)), dexmedetomidine, ketorolac, morphine (Opioid; binds mu-opioid receptors to relieve pain)

Drug routes

oral, infusion

Endpoints

Primary: Median Pain Scores in the Post-Anesthesia Care Unit, Post Operative Anesthesia Unit Length of Stay (hours), Post-operative pain at 12-24 hours

Secondary: Intraoperative Blood pressure (mmHg), Intraoperative Heart rate (beats per second)

Body systems

Psychiatry / Mental Health