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Study details
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Improving Sleep and Reducing Opioid Use in Individuals With Chronic Pain

University of South Florida
NCT IDNCT06345872ClinicalTrials.gov data as of Apr 2026
Target enrollment

165

Study length

about 3.6 years

Ages

18+

Locations

1 site in FL

About this study

This trial is testing two behavioral interventions for chronic insomnia in individuals with chronic pain. The goal is to see if improving sleep and decreasing arousal leads to normalized brain activation and reduced opioid use.

Based on ClinicalTrials.gov records.

What participants do

  • 1.Participate in CBT-I
  • 2.Participate in Treatment as usual
  • 3.Tapered Withdrawal
Primary goalChange in Fatigue - Daily Electronic Sleep Diaries

Participation effort

Estimated from trial records. Details can vary by site.

Time + visits
Low8%
Logistics
Moderate50%

Logistics difficulty varies by site location and availability.

Trial highlights

Treatment details

Auto-extracted from trial records to preview treatments and outcomes.

Endpoints

Primary: Change in Fatigue - Daily Electronic Sleep Diaries, Change in Insomnia Severity Index, Change in Neural Imaging: Structural/Functional MRI/Diffusion Weighted Imaging, Change in Pain Intensity - Daily Electronic Sleep Diaries, Change in Perceived Stress Scale, Change in Sleep and Pain Medication - Daily Electronic Sleep Diaries, Change in Thermal Pain Response

Secondary: Change in Neural Connectivity: Structural/Functional MRI/Diffusion Weighted Imaging, Change in Pain Catastrophizing Scale

Body systems

Psychiatry / Mental Health