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Study details
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Enhancing Brain Connectivity in Schizophrenia Through Neuromodulation (Trial 1)

The University of Texas Health Science Center, Houston
NCT IDNCT06345963ClinicalTrials.gov data as of Apr 2026
Target enrollment

120

Study length

about 5.9 years

Ages

18–60

Locations

1 site in TX

About this study

This trial is testing a treatment to improve brain connectivity in people with schizophrenia. The treatment involves using a device called an H-coil to deliver rTMS, which stimulates the brain. It aims to see if this approach can help strengthen connections between different parts of the brain.

Based on ClinicalTrials.gov records.

What participants do

  • 1.Use active H-coil delivered rTMS
Primary goalBrain connectivity as indicated by resting-state functional connectivity (rsFC) values as assessed by functional MRI (fMRI)

Participation effort

Estimated from trial records. Details can vary by site.

Time + visits
Low10%
Logistics
Moderate50%

Logistics difficulty varies by site location and availability.

Trial highlights

Treatment details

Auto-extracted from trial records to preview treatments and outcomes.

Endpoints

Primary: Brain connectivity as indicated by resting-state functional connectivity (rsFC) values as assessed by functional MRI (fMRI), Brain microstructural integrity as indicated by white matter fractional anisotropy (FA) values as assessed by magnetic resonance imaging (MRI)

Secondary: Depression as assessed by the Beck Depression Inventory, Depression as assessed by the Calgary Depression Scale

Devices

therapeutic

Body systems

Psychiatry / Mental Health