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Study details
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Adversity, Brain and Opioid Use Study

University of Michigan
NCT IDNCT06355778ClinicalTrials.gov data as of Apr 2026
Target enrollment

185

Study length

about 3.3 years

Ages

18–55

Locations

1 site in MI

About this study

This trial is testing how adverse childhood experiences and opioid use disorder symptoms affect brain function. Participants will complete computer tasks and have MRI scans to measure learning and memory performance. It compares three groups: adults with opioid use disorder on buprenorphine, adults without opioid use disorder on buprenorphine, and healthy adults not taking buprenorphine.

Based on ClinicalTrials.gov records.

What participants do

  • 1.Participate in Computer Tasks
  • 2.Undergo Magnetic Resonance Imaging (MRI)

Participation effort

Estimated from trial records. Details can vary by site.

Time + visits
Low8%
Logistics
Moderate50%

Logistics difficulty varies by site location and availability.

Trial highlights

Treatment details

Auto-extracted from trial records to preview treatments and outcomes.

Procedures

imaging

Body systems

Psychiatry / Mental Health