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Study details
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Non-invasive Vagal Nerve Stimulation as Novel Treatment to Improve Functional Outcomes in Veterans With Alcohol Use Disorder

VA Office of Research and Development
NCT IDNCT06399653ClinicalTrials.gov data as of Apr 2026
Target enrollment

80

Study length

about 4.7 years

Ages

21–65

Locations

1 site in CA

About this study

This trial is testing a new treatment for alcohol use disorder (AUD) that uses non-invasive vagus nerve stimulation. The goal is to see if this treatment can improve how well veterans with AUD function and their quality of life.

Based on ClinicalTrials.gov records.

What participants do

  • 1.Use Cervical transcutaneous vagus nerve stimulation (active comparator)
  • 2.Use Cervical transcutaneous vagus nerve stimulation (sham comparator)
Primary goalHamilton Anxiety Rating Scale (HAM-A)

Participation effort

Estimated from trial records. Details can vary by site.

Time + visits
Low9%
Logistics
Moderate50%

Logistics difficulty varies by site location and availability.

Trial highlights

Treatment details

Auto-extracted from trial records to preview treatments and outcomes.

Endpoints

Primary: Hamilton Anxiety Rating Scale (HAM-A), WHO Quality of Life assessment (WHOQOL-BREF)

Secondary: Neural response to heat pain fMRI task

Devices

therapeutic

Body systems

Psychiatry / Mental Health