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Study details
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Imaging Depression in Parkinson's Disease

Yale University
NCT IDNCT06402955ClinicalTrials.gov data as of Apr 2026
Phase

Phase 2

Target enrollment

120

Study length

about 4.1 years

Ages

40–80

Locations

1 site in CT

About this study

Researchers are testing whether imaging can help identify the brain areas that cause depression in people with Parkinson's disease. The trial will use scans to look at how different parts of the brain are working when people experience depression. It involves adults aged 40-80 experiencing symptoms of depression.

Based on ClinicalTrials.gov records.

What participants do

  • 1.Receive 11C-UCB-J
  • 2.Take ketamine hydrochloride
PhasePhase 2
Drugketamine hydrochloride
Primary goalMontgomery-Åsberg Depression Rating Scale (MADRS)

Participation effort

Estimated from trial records. Details can vary by site.

Time + visits
Low13%
Logistics
Moderate50%

Logistics difficulty varies by site location and availability.

Trial highlights

Treatment details

Auto-extracted from trial records to preview treatments and outcomes.

Drug classes

Anesthetics (Dopamine Agonists)

Endpoints

Primary: Montgomery-Åsberg Depression Rating Scale (MADRS)

Body systems

Neurology, Psychiatry / Mental Health