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Study details
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Study of Oral Ubrogepant to Assess Adverse Events and Change in Disease Activity in Adult Participants With Menstrual Migraine

AbbVie
NCT IDNCT06417775ClinicalTrials.gov data as of Apr 2026
Phase

Phase 3

Target enrollment

496

Study length

about 3.1 years

Ages

18+

Sex

Female only

Locations

103 sites in AL, AR, AZ +36

About this study

Researchers are testing a treatment called ubrogepant for menstrual migraine. The trial is testing how safe and effective ubrogepant is in treating menstrual migraine. Participants will take either ubrogepant or a placebo daily for 16 weeks, then may continue with ubrogepant for another 52 weeks.

Based on ClinicalTrials.gov records.

What participants do

  • 1.Take Placebo for Ubrogepant
  • 2.Take Ubrogepant
PhasePhase 3
DrugUbrogepant
Routeoral
Primary goalChange From Baseline in Number of Migraine Days Occurring During Perimenstrual Periods (PMPs) Across the Double-Blind Treatment Period

Participation effort

Estimated from trial records. Details can vary by site.

Time + visits
Low3%
Logistics
Moderate50%

Logistics difficulty varies by site location and availability.

Trial highlights

Treatment details

Auto-extracted from trial records to preview treatments and outcomes.

Drug classes

ubrogepant

Drug routes

oral (Oral Tablet)

Endpoints

Primary: Change From Baseline in Number of Migraine Days Occurring During Perimenstrual Periods (PMPs) Across the Double-Blind Treatment Period, Number of Participants With Adverse Events (AEs)

Secondary: Change From Baseline in Acute Medication Use Days During the Perimenstrual Periods (PMPs) Across the Double-Blind Treatment Period, Change From Baseline in Number of Headache Days Occurring During Perimenstrual Periods (PMPs) Across the Double-Blind Treatment Period, Change From Baseline in Number of Migraine Days With Moderate or Severe Headache During Perimenstrual Periods (PMPs) Across the Double-Blind Treatment Period, Change From Baseline in Number of Moderate or Severe Headache Days During Perimenstrual Periods (PMPs) Across the Double-Blind Treatment Period

Body systems

Neurology