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Study details
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A Study of Tirzepatide in Adolescents With Obesity and Weight-Related Comorbidities (SURMOUNT-ADOLESCENTS-2)

Eli Lilly and Company
NCT IDNCT06439277ClinicalTrials.gov data as of Apr 2026
Phase

Phase 3

Target enrollment

300

Study length

about 6.6 years

Ages

12–17

Locations

15 sites in CA, DE, GA +6

About this study

Researchers are testing tirzepatide, a medication, to see how it affects weight and heart health in adolescents with obesity and related conditions. The trial will last about 76 weeks and may include up to 23 visits.

Based on ClinicalTrials.gov records.

What participants do

  • 1.Take Placebo
  • 2.Take Tirzepatide
PhasePhase 3
DrugTirzepatide
Routeinjection
Primary goalPercent Change from Baseline in Body Mass Index (BMI)

Participation effort

Estimated from trial records. Details can vary by site.

Time + visits
Low7%
Logistics
Moderate50%

Logistics difficulty varies by site location and availability.

Trial highlights

Treatment details

Auto-extracted from trial records to preview treatments and outcomes.

Drug classes

tirzepatide

Drug routes

injection (Injection)

Endpoints

Primary: Percent Change from Baseline in Body Mass Index (BMI)

Secondary: Change from Baseline in Diastolic Blood Pressure (DBP), Change from Baseline in Hemoglobin A1c (HbA1c), Change from Baseline in Peripheral Apnea-Hypopnea Index (pAHI), Change from Baseline in Systolic Blood Pressure (SBP), Change from Baseline in Waist Circumference, Percent Change from Baseline in Body Weight, Percent Change from Baseline in Total Body Fat Mass as Determined by Dual energy X-ray Absorptiometry (DXA), Percent Change from Baseline in Triglycerides

Body systems

Endocrinology