ACTION Trial
Phase 1/2
240
about 4.6 years
18+
1 site in SC
About this study
Researchers are testing whether adding buprenorphine, CBT, and TMS to long-term opioid therapy can improve outcomes for people with chronic pain. The trial will evaluate three interventions: a low dose of buprenorphine without withdrawal, a brief Cognitive Behavioral Intervention (CBI), and accelerated rTMS over the left dorsolateral prefrontal cortex. Participants will be followed for 1692 days.
Based on ClinicalTrials.gov records.
What participants do
- 1.Take Buprenorphine Patch
- 2.Take Placebo
- 3.Use Sham Transcranial Magnetic Stimulation (TMS)
- +1 more
Participation effort
Estimated from trial records. Details can vary by site.
Logistics difficulty varies by site location and availability.
Trial highlights
Treatment details
Auto-extracted from trial records to preview treatments and outcomes.
buprenorphine
sublingual, transdermal
Primary: Buprenorphine Tolerability, Pain Severity -with Buprenorphine Patch
Secondary: Quality of Life -with Buprenorphine Patch
therapeutic
Psychiatry / Mental Health