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Study details
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Precision Administration of Anti-thymocyte Globulin With or Without Verapamil

University of Florida
NCT IDNCT06455319ClinicalTrials.gov data as of Apr 2026
Phase

Phase 2

Target enrollment

60

Study length

about 4.8 years

Ages

6–35

Locations

2 sites in CO, FL

About this study

This trial is testing a new way to treat type 1 diabetes. It involves using anti-thymocyte globulin (ATG) with or without verapamil, and it aims to improve how well the treatment works for each person. The goal is to find better ways to manage type 1 diabetes by understanding what makes people respond differently to the treatment.

Based on ClinicalTrials.gov records.

What participants do

  • 1.Take Anti-thymocyte globulin (ATG)
  • 2.Take Placebo
  • 3.Take verapamil extended release capsule
PhasePhase 2
Drugverapamil extended release capsule
Routeoral
Primary goalAUC C-peptide between ATG and placebo values

Participation effort

Estimated from trial records. Details can vary by site.

Time + visits
Low12%
Logistics
Moderate50%

Logistics difficulty varies by site location and availability.

Trial highlights

Treatment details

Auto-extracted from trial records to preview treatments and outcomes.

Drug classes

verapamil (Calcium channel blocker; slows heart rate and dilates vessels)

Drug routes

oral

Endpoints

Primary: AUC C-peptide between ATG and placebo values, Change in 2-hr MMTT AUC C-peptide

Body systems

Endocrinology