Study details
Enrolling now
Standard Versus High Dose ED-Initiated Buprenorphine Induction
Yale University
NCT IDNCT06494904ClinicalTrials.gov data as of Apr 2026
Phase
Phase 3
Target enrollment
360
Study length
about 4.1 years
Ages
18–65
Locations
5 sites in CA, ME, NJ +1
About this study
Researchers are testing whether a higher dose of buprenorphine, started in the emergency department (ED), helps more people start opioid treatment sooner than a standard dose. The trial will also measure how much withdrawal symptoms and cravings are reduced with both doses.
Based on ClinicalTrials.gov records.
What participants do
- 1.Take Buprenorphine
PhasePhase 3
DrugBuprenorphine
Routeinjection
Participation effort
Estimated from trial records. Details can vary by site.
Time + visits
Low9%
Logistics
Moderate50%
Logistics difficulty varies by site location and availability.
Trial highlights
Treatment details
Auto-extracted from trial records to preview treatments and outcomes.
Drug classes
buprenorphine
Drug routes
injection
Body systems
Psychiatry / Mental Health