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Study details
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Empagliflozin Trial to Reduce Arterial Stiffness in Older Adults

University of Missouri-Columbia
NCT IDNCT06506422ClinicalTrials.gov data as of Apr 2026
Phase

Phase 2/3

Target enrollment

80

Study length

about 4.5 years

Ages

60–80

Locations

1 site in MO

About this study

Researchers are testing whether empagliflozin, a medication, can help reduce arterial stiffness in older adults. The trial involves randomly assigning participants aged 60-80 to either empagliflozin or a placebo for 12 weeks. It will last approximately 1655 days.

Based on ClinicalTrials.gov records.

What participants do

  • 1.Take Empagliflozin 10 MG
  • 2.Take Placebo
PhasePhase 2/Phase 3
DrugEmpagliflozin 10 MG
Primary goalCarotid Femoral Pulse Wave Velocity (cfPWV)

Participation effort

Estimated from trial records. Details can vary by site.

Time + visits
Low10%
Logistics
Moderate50%

Logistics difficulty varies by site location and availability.

Trial highlights

Treatment details

Auto-extracted from trial records to preview treatments and outcomes.

Drug classes

empagliflozin (SGLT2 inhibitor; increases glucose excretion in urine)

Endpoints

Primary: Carotid Femoral Pulse Wave Velocity (cfPWV)