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Study details
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Study to Assess Tezampanel for Opioid Withdrawal Syndrome

Proniras Corporation
NCT IDNCT06538558ClinicalTrials.gov data as of Apr 2026
Phase

Phase 1

Target enrollment

40

Study length

about 1.1 years

Ages

18–65

Locations

1 site in IN

About this study

This trial is testing whether Tezampanel (TZP) can help with opioid withdrawal syndrome in people who have opioid use disorder. Participants will receive either TZP or a placebo daily for 7 days during their stay at the research center.

Based on ClinicalTrials.gov records.

What participants do

  • 1.Take Placebo
  • 2.Take Tezampanel
PhasePhase 1
Primary goalTo evaluate systemic tolerability and safety of intravenous tezampanel administration

Participation effort

Estimated from trial records. Details can vary by site.

Time + visits
Low13%
Logistics
Moderate50%

Logistics difficulty varies by site location and availability.

Trial highlights

Treatment details

Auto-extracted from trial records to preview treatments and outcomes.

Endpoints

Primary: To evaluate systemic tolerability and safety of intravenous tezampanel administration.

Secondary: To characterize Area Under the Curve (AUC) concentration of tezampanel, To characterize Cmax (maximum concentration) of tezampanel

Body systems

Psychiatry / Mental Health