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Study details
Enrolling now

Combined THC and CBD for OUD and Chronic Pain

Yale University
NCT IDNCT06544291ClinicalTrials.gov data as of Apr 2026
Phase

Phase 2

Target enrollment

147

Study length

about 3.3 years

Ages

18–65

Locations

1 site in CT

About this study

This trial is testing a treatment with combined THC and CBD to help people with opioid use disorder (OUD) and chronic pain. The goal is to see if this treatment reduces both pain and cravings for opioids.

Based on ClinicalTrials.gov records.

What participants do

  • 1.Take CBD 300mg
  • 2.Take CBD 600mg
  • 3.Take Placebo 0mg
PhasePhase 2
DrugCBD 300mg
Primary goalPrimary Outcome Variable #1: Pain Sensitivity

Participation effort

Estimated from trial records. Details can vary by site.

Time + visits
Low14%
Logistics
Moderate50%

Logistics difficulty varies by site location and availability.

Trial highlights

Treatment details

Auto-extracted from trial records to preview treatments and outcomes.

Drug classes

cannabinoid

Endpoints

Primary: Primary Outcome Variable #1: Pain Sensitivity

Secondary: Secondary Outcome Variable #3a: Monitor adverse events from the study medications (SAFTEE), Secondary Outcome Variable #3b: Monitor adverse events from the study medications (Cardiovascular)

Body systems

Psychiatry / Mental Health