Physiologic Response to Bariatric Surgery and the Impact of Adjunct Semaglutide in Adolescents
Phase 1
48
about 3 years
12–24
1 site in CO
About this study
Researchers are testing how the body changes after bariatric surgery in adolescents. The trial will investigate why some people respond differently to this surgery and if a medication (semaglutide) can help adolescents who haven't lost enough weight after 1-2 years of bariatric surgery.
Based on ClinicalTrials.gov records.
What participants do
- 1.Participate in Standard postoperative care
- 2.Receive Injectable semaglutide
Participation effort
Estimated from trial records. Details can vary by site.
Logistics difficulty varies by site location and availability.
Trial highlights
Treatment details
Auto-extracted from trial records to preview treatments and outcomes.
semaglutide (GLP-1 agonist; stimulates insulin release)
oral (Oral Tablet), injection
Primary: Intervention phase: Change in BMI, Observational phase: Change in 24 hour systolic blood pressure (BP), measured by ambulatory BP monitor
Secondary: Change in 24 hour systolic blood pressure (BP), measured by ambulatory BP monitor, Intervention Phase: Number of participants with an adverse event (AE) that leads to discontinuation of the medication, measured by a count, Intervention Phase: Number of participants with at least one serious adverse event (AE) in the active medication group, measured by a count
Endocrinology