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Study details
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Hyperbaric Oxygen Treatment for Veterans With Traumatic Brain Injury

University of South Florida
NCT IDNCT06581003ClinicalTrials.gov data as of Apr 2026
Phase

Phase 3

Target enrollment

420

Study length

about 4.9 years

Ages

18–75

Locations

1 site in FL

About this study

Researchers are testing whether hyperbaric oxygen therapy (HBOT) can help improve symptoms in veterans and active military with mild to moderate traumatic brain injury. The trial will compare HBOT to a placebo condition, where participants breathe normal air. Participants will receive 40 sessions of either HBOT or the placebo over 12 weeks.

Based on ClinicalTrials.gov records.

What participants do

  • 1.Take Oxygen 21 %
  • 2.Take Oxygen 99.7 %
PhasePhase 3
DrugOxygen 99.7 %
Primary goalChange from Baseline in the Neurobehavioral Symptoms at 2 weeks Post Intervention

Participation effort

Estimated from trial records. Details can vary by site.

Time + visits
Low9%
Logistics
Moderate50%

Logistics difficulty varies by site location and availability.

Trial highlights

Treatment details

Auto-extracted from trial records to preview treatments and outcomes.

Drug classes

oxygen

Endpoints

Primary: Change from Baseline in the Neurobehavioral Symptoms at 2 weeks Post Intervention

Secondary: Change from Baseline in post traumatic stress disorder symptoms at 2 weeks post intervention