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Study details
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A Phase 1 Dose Escalation Trial of ZG006 in Patients With Small Cell Lung Cancer

Suzhou Zelgen Biopharmaceuticals Co.,Ltd
NCT IDNCT06592638ClinicalTrials.gov data as of Apr 2026
Phase

Phase 1

Target enrollment

30

Study length

about 2.2 years

Ages

18–75

Locations

6 sites in CA, FL, KY +2

About this study

This trial is testing a treatment called ZG006 for people with small cell lung cancer who have not responded to or cannot tolerate standard treatments. The goal is to find the best dose of ZG006 that can be safely used in future studies.

Based on ClinicalTrials.gov records.

What participants do

  • 1.Take ZG006
PhasePhase 1
Primary goalMaximum Tolerated Dose (MTD) of ZG006

Participation effort

Estimated from trial records. Details can vary by site.

Time + visits
Low12%
Logistics
Moderate50%

Logistics difficulty varies by site location and availability.

Trial highlights

Treatment details

Auto-extracted from trial records to preview treatments and outcomes.

Endpoints

Primary: Maximum Tolerated Dose (MTD) of ZG006, Number of participants with adverse events (AEs), Number of participants with serious adverse events (SAEs), The incidence of dose-limiting toxicity (DLT)

Secondary: AUC from time zero to the last quantifiable concentration after dosing (AUC[0-t]) of ZG006, Disease control rate (DCR), Duration of response (DOR), Maximum plasma concentration (Cmax) of ZG006, Objective response rate (ORR), Terminal phase half-life (t1/2) of ZG006, Time to peak concentration (Tmax)

Body systems

Oncology