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Study details
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A Study to Learn About the Study Medicine Called Rimegepant in Adolescents With Frequent Migraine

Pfizer
NCT IDNCT06616194ClinicalTrials.gov data as of Apr 2026
Phase

Phase 3

Target enrollment

200

Study length

about 3 years

Ages

12–17

Locations

26 sites in AZ, CA, CO +12

About this study

Researchers are testing a treatment called rimegepant for adolescents with frequent migraine attacks. The trial will last 1112 days and involve comparing rimegepant to an inactive tablet, as well as long-term use of rimegepant. Participants will keep a daily diary of their migraines.

Based on ClinicalTrials.gov records.

What participants do

  • 1.Take Placebo
  • 2.Take Rimegepant
PhasePhase 3
DrugRimegepant
Routeoral

Participation effort

Estimated from trial records. Details can vary by site.

Time + visits
Low4%
Logistics
Moderate50%

Logistics difficulty varies by site location and availability.

Trial highlights

Treatment details

Auto-extracted from trial records to preview treatments and outcomes.

Drug classes

rimegepant

Drug routes

oral (Disintegrating Oral Tablet)

Endpoints

Secondary: Efficacy of rimegepant relative to placebo measure as the mean change from baseline in the number of acute headache medication days per month, and acute migraine-specific medication days per month, Efficacy of rimegepant relative to placebo measured as mean change from baseline in the PedMIDAS total score, Efficacy of rimegepant relative to placebo measured as the mean change from baseline in the Pediatric Quality of Life (PedsQL™) total score, Efficacy of rimegepant relative to placebo measured as the mean change from baseline in the number of acute migraine-specific medication days per month, Efficacy of rimegepant relative to placebo measured the mean change from baseline in the number of headache days per month, Safety of rimegepant relative to placebo, and safety of rimegepant given for a long period of time measured as the number and percentage of participants with adverse event by severity and overall, Safety of rimegepant relative to placebo, and safety of rimegepant given for long period of time measured as the number and percentage of participants with liver-related adverse event and action taken

Body systems

Neurology