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Study details
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A Study Evaluating the Safety and Efficacy of Glofitamab + Gemcitabine + Oxaliplatin in U.S. Patients With Relapsed or Refractory Diffuse Large B-Cell Lymphoma

Hoffmann-La Roche
NCT IDNCT06624085ClinicalTrials.gov data as of Apr 2026
Phase

Phase 1

Target enrollment

50

Study length

about 4.9 years

Ages

18+

Locations

15 sites in CA, DC, FL +8

About this study

Researchers are testing a treatment with glofitamab, gemcitabine, and oxaliplatin for people in the United States who have relapsed or refractory diffuse large B-cell lymphoma. The trial will last about 1798 days.

Based on ClinicalTrials.gov records.

What participants do

  • 1.Take Gemcitabine
  • 2.Take Glofitamab
  • 3.Take Obinutuzumab
  • +2 more
PhasePhase 1
DrugGemcitabine
Routeinjection
Primary goalComplete response (CR) rate

Participation effort

Estimated from trial records. Details can vary by site.

Time + visits
Low15%
Logistics
Moderate50%

Logistics difficulty varies by site location and availability.

Trial highlights

Treatment details

Auto-extracted from trial records to preview treatments and outcomes.

Drug classes

gemcitabine, glofitamab, obinutuzumab, oxaliplatin, tocilizumab (Monoclonal antibody; blocks IL-6 receptor to reduce inflammation)

Drug routes

injection (Injection), injection, intravenous, infusion

Endpoints

Primary: Complete response (CR) rate, Incidence of Adverse Events (AEs)

Secondary: Duration of CR, Duration of response (DOR), Objective response rate (ORR), Overall Survival (OS), Progression-free survival (PFS)

Body systems

Oncology