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Study details
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A Study of JNJ-90301900 in Combination With Chemoradiation Followed by Consolidation Immunotherapy for Non-Small Cell Lung Cancer (NSCLC)

Johnson & Johnson Enterprise Innovation Inc.
NCT IDNCT06667908ClinicalTrials.gov data as of Apr 2026
Phase

Phase 2

Target enrollment

130

Study length

about 4.1 years

Ages

18+

Locations

15 sites in CT, FL, GA +8

About this study

Researchers are testing whether adding a treatment to chemotherapy and radiation therapy, followed by immunotherapy, can improve the response rate in people with advanced lung cancer. The trial will last about 1486 days.

Based on ClinicalTrials.gov records.

What participants do

  • 1.Receive Concurrent Chemo/Radiation Therapy (cCRT)
  • 2.Receive Durvalumab
  • 3.Take Concurrent Chemo/Radiation Therapy (cCRT): Carboplatin
  • +2 more
PhasePhase 2
DrugConcurrent Chemo
Routeinfusion
Primary goalObjective Response Rate (ORR) Using Independent Central Review (ICR) Assessment

Participation effort

Estimated from trial records. Details can vary by site.

Time + visits
Low13%
Logistics
Moderate50%

Logistics difficulty varies by site location and availability.

Trial highlights

Treatment details

Auto-extracted from trial records to preview treatments and outcomes.

Drug classes

chemotherapy, durvalumab

Drug routes

infusion

Endpoints

Primary: Objective Response Rate (ORR) Using Independent Central Review (ICR) Assessment

Secondary: Disease Control Rate (DCR) Post-cCRT and Pre-cIT, Duration of Response (DoR), Number of Participants Reporting Laboratory Parameters, Physical Examination, Vital Signs Including Eastern Cooperative Oncology Group (ECOG) Performance Status Abnormalities, Number of Participants with Treatment-Emergent Adverse Event (TEAE) Related to Study Treatment, Objective Response Rate (ORR) Post-cCRT and Pre-cIT, Objective Response Rate (ORR) as Assessed by the Investigator, Progression Free Survival (PFS)

Procedures

radiation

Body systems

Oncology